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@arXiv_qbioOT_bot@mastoxiv.page
2024-03-07 07:26:56

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling
Hanwen WangDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA, Theinmozhi ArulrajDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA, Alberto IppolitoDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA, A…

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling
Virtual patients and digital patients/twins are two similar concepts gaining increasing attention in health care with goals to accelerate drug development and improve patients' survival, but with their own limitations. Although methods have been proposed to generate virtual patient populations using mechanistic models, there are limited number of applications in immuno-oncology research. Furthermore, due to the stricter requirements of digital twins, they are often generated in a study-specific…

@thomasfuchs@hachyderm.io
2024-02-27 02:53:15

“hesitating to give chemotherapy to cancer patients”
Again I ask you to ostracize your Republican family and “friends” unless they extract themselves from this death cult.

Osmundson and 30 other doctors across nine states in which abortion is banned or restricted described to ProPublica the impossible landscape they must navigate in the nearly two years since the Supreme Court struck down Roe v. Wade. It is one in which fetuses - some with no chance of survival - are being prioritized over their at-risk mothers and oncologists are hesitating to give chemotherapy to cancer patients for fear of legal consequences if it disrupts the pregnancies.
@baruch@babka.social
2024-03-26 15:34:22

Innovative Jewish community leader Yocheved Sidof (#Purim

A woman wearing a headscarf and large earrings shares a mix of reflections about the Purim that we just celebrated: Some words of gratitude for the Ohmek Living community, reflections on her ancestors and their connection to the holiday, her decision to read the Megillah this year, and the idea that Mordechai expressed to Esther: Who knows if this is what you were born for? Esther lived her life as a walking prayer, and we must follow her example.

Ohmek Living - Ohmek Living
BS”D allpossibilities present ABOUT OHMEK a        place to        be Ohmek is a community of women and men pursuing deeper ways of being. At our upstate retreat center and Brooklyn locations, we invite you into spiritual experiences and sacred spaces that allow us — collectively and individually — to explore […]

@vosje62@mastodon.nl
2024-04-18 18:52:08

Qué? Zeeman bezorgt per ongeluk Spaanse folders | #RTLnl
rtl.nl/nieuws/artikel/5446173/

Qué? Zeeman bezorgt per ongeluk Spaanse folders
Je moet er een eind voor rijden, maar dan heb je ook wat. Textielwinkel Zeeman heeft in Den Haag reclamefolders laten bezorgen, die eigenlijk voor Spanje bedoeld waren. Met de folder werd geadverteerd voor een nieuwe winkel in Premia de Mar, Catalonië.

@roelgrif@mstdn.social
2024-03-13 09:38:00

Sappen zijn al uitgezonderd als deze slechts 0,02 procent melkvet bevatten. 'Je bent dus echt gek als je niet een klein beetje zuivel toevoegt als sapfabrikant.'
Ongelofelijk wat een dommigheid van de wetgever. En als vegan ben je in de aap gelogeerd als dit een grote vlucht gaat nemen.

Appelsientje ontwijkt suikertaks met truc: vleugje zuivel maakt sap belastingvrij
Appelsientje weet met een truc de pas verhoogde suikertaks te omzeilen, blijkt uit onderzoek van BNR. De sapfabrikant hoeft de belasting niet te betalen omdat aan een nieuw product een klein beetje zuivel is toegevoegd.

@ErikJonker@mastodon.social
2024-04-09 14:28:11

Leuk artikel van Chris Klomp.
#ChrisKlomp

Wat populariteit pestkop Wilders zegt over onszelf - Chris Klomp
De populariteit van Wilders is op verschillende manieren te verklaren. Onvrede over bestaand beleid bijvoorbeeld en partijen die het niet voor elkaar krijgen om problemen op te lossen. Maar ik wil het over iets anders hebben. Hoe kan het dat zoveel mensen kennelijk geen moeite hebben met het sarren, demoniseren en kleineren? Mijn conclusie is […]

@toxi@mastodon.thi.ng
2024-04-24 21:39:52

Fantasy console update: Just added & polished some more of these examples from last year and you can play with them here:
demo.thi.ng/umbrella/fantasy-c
Instructions:
- Press `1` - `6` to select/launch/reset any of the examples
- Press …

Short sequence of screenshots of the 6 example projects described in the toot.
@arXiv_physicsmedph_bot@mastoxiv.page
2024-03-06 07:19:24

Characterization of a novel time-resolved, real-time scintillation dosimetry system for ultra-high dose rate radiation therapy applications
Alexander BaikalovDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, Department of Radiation Oncology, School of Medicine and Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, Institute of Radiation Medicine, Helmholtz Zentrum M\"unchen GmbH, German Research …

Characterization of a novel time-resolved, real-time scintillation dosimetry system for ultra-high dose rate radiation therapy applications
Background: Scintillation dosimetry has promising qualities for ultra-high dose rate (UHDR) radiotherapy (RT), but no system has shown compatibility with mean dose rates ($\bar{DR}$) above 100 Gy/s and doses per pulse ($D_p$) exceeding 1.5 Gy typical of UHDR (FLASH)-RT. The aim of this study was to characterize a novel scintillator dosimetry system with the potential of accommodating UHDRs. Methods: A thorough dosimetric characterization of the system was performed on an UHDR electron beamline.…

@beaware@social.beaware.live
2024-03-04 11:17:29

This is pretty spot on...
#ADHD #neurodivergent #neurodiversity #neurodiverse

A comic strip that serves as a friendly guide on ADHD-related behaviors, cautioning that it doesn’t replace a professional diagnosis. It illustrates various situations familiar to those with ADHD: difficulty in applying oneself, procrastination even with enjoyable tasks, a skewed perception of time, hyperfocus causing basic needs to be forgotten, impatience with others’ thought processes, self-doubt about laziness, heightened emotional responses, a relentless boredom that’s hard to satisfy, fee…
@vosje62@mastodon.nl
2024-04-18 18:52:08

Qué? Zeeman bezorgt per ongeluk Spaanse folders | #RTLnl
rtl.nl/nieuws/artikel/5446173/

Qué? Zeeman bezorgt per ongeluk Spaanse folders
Je moet er een eind voor rijden, maar dan heb je ook wat. Textielwinkel Zeeman heeft in Den Haag reclamefolders laten bezorgen, die eigenlijk voor Spanje bedoeld waren. Met de folder werd geadverteerd voor een nieuwe winkel in Premia de Mar, Catalonië.